Wearable Continuous Point-of-Care Monitoring, Risk Estimation and Prevention for Deep Vein Thrombosis

ThrombUS+ is a €9.5 million project funded by the European Commission focusing on early diagnosis and prevention of deep vein thrombosis (DVT) of the lower limbs, a common and life-threatening condition.

Our goal is to create a groundbreaking smart wearable device that will bring together the latest technologies of the different partners to continuously and autonomously monitor the lower limbs to detect clot formation, estimate the risk of thrombosis and create early alerts.

This device will use autonomous AI-driven DVT detection and combine wearable ultrasound hardware, impedance plethysmography, and light reflection rheography to quickly detect blood clots.
In addition, it will also continuously measure activity and physiological data to assess the risk of DVT and support prevention through serious gaming.

ThrombUS+ device will be suitable for postoperative patients, those undergoing lengthy surgical procedures, cancer patients, bedridden individuals at home or in care units, and women during pregnancy and postpartum.

ThrombUS+ will use large datasets from three clinical studies for AI training. One early feasibility study and one multi-centre clinical trial will validate the results.

ComfTech, with its extensive experience in smart textiles and wearable technology, will make a valuable contribution.
We will coordinate the definition of architectural design of the wearable, which will serve as a guide for the next stages of the project and then we will work alongside other partners to integrate sensors and hardware into a wearable system that not only meets technical and functional requirements but also ensures comfort and wearability for end-users.

The project will span over a period of 42 months and will involve 18 partners from various countries:

– ATHENA Research and Innovation Center in Information, Communication and Knowledge Technologies, Greece
– KTU Kaunas University of Technology, Lithuania
– VERMON SA, France
– FRAUNHOFER Institute for Photonic Microsystems, Germany
– TELEMED Telemed Ultrasound Medical Systems, Lithuania
– EchoNous Inc, USA
– MEDIS Medizinische Messtechnik GmbH, Germany
– ComfTech srl, Italy
– TAU Faculty of Medicine and Health Technology, Tampere University, Finland
– Lithuanian University of Health Science, Lithuania
– Papageorgiou General Hospital, Greece
– CSS-IRCCS Casa Sollievo della Sofferenza, Italy
– Simon Veil Hospital, France
– VDE Association for Electrical, Electronic & Information Technologies, Germany
– MEDEA srl, Italy
– PHAZE Clinical Research and Pharma Consulting SA, Greece
– PredictBy Research and Consulting SL, Spain
– SciGen Technologies SA, Greece


Horizon Innovation Action | Agreement No. 101137227 HORIZON-HLTH-2023-TOOL-05-05 Co-funded by the European Union